Rab2 drives axonal transport of dense core vesicles and lysosomal organelles
Summary: Fast axonal transport of neuropeptide-containing dense core vesicles (DCVs), endolysosomal organelles, and presynaptic components is critical for maintaining neuronal functionality.How the transport of DCVs is orchestrated remains an important unresolved question.The small GTPase Rab2 mediates DCV biogenesis and endosome-lysosome fusion.He